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C60 Research

Please book mark this C60 Research page as it is continuously being updated as new studies and information become available.

C60 Fullerenes, are a newly discovered natural Carbon molecule in the shape of a spherical ball, made of sixty carbon atoms.  Since being discovered in 1985, C60 has taken the medical & scientific research world by storm. Countless studies have shown that C60 Fullerene Molecules (also nick named “Buckyballs”) exhibit incredible potential uses in biology and medicine, including UV and radioprotection, antioxidant activities, free radical scavengers, antiviral  & antibacterial, allergic response inhibitions, immune stimulating and anti-tumour effects, gene delivery, and even hair-growing activity.

Image result for c60

During the past over 20 years that I have been making and researching natural skincare, I have been searching for the “ultimate delivery system”.  Let me explain:  When we are dealing with the skin, no matter if it’s on your face or your feet, no matter if it’s the highest quality oils and essences or cheap crappy lotion from the dollar store, whatever you apply to the skin will only absorb a certain depth into the layers of the skin.  Various oil molecules have different ratios of absorption and the size and shape of the molecules have a large effect on just how deeply they will saturate the skins outer tissue.  For example, mineral oil is found in almost EVERY commercial body/facial moisturizer on the planet- it’s a cheap filler. Mineral oils has quite a large molecule and only absorbs through the very top layer of dead skin cells… the rest just lays on the surface of the skin, giving the illusion of “moisture”. When we look at where skin problems begin, be it acne, wrinkles, eczema, or even allergic dermatitis, it almost always starts in the deeper epidermis layers of our skin, where oils and essential oils really cannot reach.  So we treat the surface epidermis the best that we can, and continuously search for a delivery system that will allow for deeper penetration of oils and essences, delivering the “package” to the tissues that really need it most.

There have been contenders for the position of delivery driver, but most have been made with highly questionable chemicals.  The one hope I had turned out to be unusable, not because it didn’t work- it most certainly DID!- but because of the side effects.  DMSO (dimethyl sulfoxide), is a potent scavenger of free radicals, and has been scientifically proven to be able to “encapsulate” medicines, oils, etc and carry them deep into the tissues… the only problem is: THE SMELL!  A single drop on your skin will instantly travel pretty much through your entire body and you will be able to TASTE it on your tongue within 1 minute, and with any amount of continuous usage, you will begin to emit the smell of garlic through your pores. This might be something that someone with serious cancer will put up with, but most of us just aren’t ready to pay that price for good skin!  And so my continuous search for the “ultimate delivery system” continued…

Late 2017 I heard about an amazing new product, a newly discovered molecule that could very well be the answer I’ve been looking for.

Enter: C60 Fullerenes.

I have spent a massive amount of hours over the past 8 months researching C60, reading hundreds of scientific and medical studies and talking to researchers about this amazing molecule.  As I said above at the beginning of this discussion, research into C60 has shown a huge amount of promise in multiple areas of health and healing: C60 is one of the best antioxidants ever researched and is a powerful free radical scavenger, along with strong antiviral and antibacterial responses, its been proven to stimulate the immune system…  The list goes on and on, and every day more studies are being done in different areas of biology, medicine and cosmetology.  There has been a huge buzz through the internet as show after show have gone viral talking about the miracle of C60.  Well known independent journalists and researchers have publicly shared tons of information about it, you only have to do a quick search on YouTube to find hours and hours of video information….

… BUT… For me, when I reviewed all of the scientific studies and the various stacks of information on C60, there were pieces of information missing, and most importantly, in my opinion, most of even the most well respected scientist were missing a huge piece of the puzzle.  The mistake that I’ve seen, across the board, is that almost ALL of the scientists and researchers have studied the C60 as a separate ingredient, without examining the major variable that was right in front of them:  The OIL.  Almost every scientist and researcher I’ve listened to and discussed C60 with, have only viewed C60 as the “miracle ingredients”, and they have shrugged off the oil that the fullerenes have been emulsified into, as nothing more than a carrier for the c60.

In my opinion this is completely BACKWARDS.   The C60 IS the “Ultimate Delivery System” for the Oils!!!

Because of this omission in perspective, vast majority of the c60 products that are currently being produced and marketed, are either made from inferior quality oils, such as commercially sold “Olive” oil (please research commercial “olive” oil, you will discover that 90% of what you see in stores is NOT Olive oil, and of the remaining 10% most of it is of radically inferior quality, from hybridized trees that have little to no medicinal value ) or Sunflower oil which carries a toxic load (yea, even “organic”) as Sunflowers are the “sponges” that draw chemicals and toxins out of the soil and groundwater, or in fractionated coconut oil, in which the fractionation process has removed most of the beneficial fatty acids and healthy components like lauric acid, rendering it into an oil that can only barely be called “coconut”.  This may not seem to be a big issue to a lot of people, but the missing pieces of the puzzle that is not talked about is that the C60 molecule when it is “dissolved” into oil, then carries that oil with it, INTO the tissues and INTO the cells and INTO the bloodstream.

Do you comprehend how important the quality of the oils being used with C60 are?

Let’s turn this around a bit and look at this from the perspective of the C60 being the actual “delivery system”.  We now have a molecule that we KNOW “dissolves” in oil, and can then carry whatever it has been loaded with, into the tissues and into the cells.  We already know about the amazing benefits of Argan Oil for the skin. We already know that it is an amazing healer, that it improves elasticity and encourages collagen production, increases skin hydration, improves skin tone & texture, and helps to smooth dehydration lines and wrinkles. We already know that Black Seed oil has unbelievable health benefits and healing properties, and there have been even more medical and scientific studies done on Black Seed  than have been done on C60!

Now imagine super boosting these healing factors with C60 Fullerenes, which will allow these oils to be actually delivered to where the health problems all began!

All of the incredible benefits of C60, combined with all the skin healing benefits of Argan oil. All the incredible benefits of C60, mixed with all of the amazing health benefits of Black Seed Oil


THIS is where old world ingredients meets new world chemistry, bringing together elements that will change how we look at health and healing.

 

Here are a few of the best research papers and scientific studies done on C60 Fullerenes:

 

This first paper is one of the most important, as it is the “story”, if you will, of several lab rats who were fed C60 Fullerenes to try and find it’s “Toxicity” levels… and they refused to die. For YEARS.

 

The prolongation of the lifespan of rats by repeated oral administration of [C60] fullerene

The_prolongation_of_the_lifespan_of_rats_by_repeat

 

This second paper is a newer study from 2017 which validates my theory about the quality of the oil that the C60 is emulsified in, in comparison to absorption:

Biological potential of nanomaterials strongly depends on the suspension media: experimental data on the effects of fullerene C60 on membranes

  Differently, by dispersing both C60 and the phospholipids in chloroform, we confirmed the possible interaction of C60 with the bilayer. We provide experimental data suggesting that the suspension medium is an important factor in determining the C60-membrane interaction, which is not always included in computational studies. Since the primary particle size is not the only crucial parameter in C60-membrane interactions, it is important to determine the most relevant characteristics of their effects on membranes.

Impacts of fullerene C60 and virgin olive oil on cadmium-induced genotoxicity in rats.

Currently, cadmium is considered to be one of the major environmental pollutants. Environmentally, cadmium is released in various forms e.g. oxide, chloride and sulphide. The aim of the present study was to examine the genotoxic impact of fullerene nanoparticles C60 (C60) and virgin olive oil (VOO) on cadmium chloride (CdCl2)-induced genotoxicity in rats. …. Surprisingly, C60 and VOO significantly attenuated the genotoxic effects caused by CdCl2 in livers and kidneys. In bone marrow, in addition to a reduction in the chromosomal number, several chromosomal aberrations were caused by CdCl2. These chromosomal alterations were also reversed by C60 and VOO. In conclusion, molecular and cytogenetic studies showed that C60 and VOO exhibit anti-genotoxic agents against CdCl2-induced genotoxicity in rats.

https://www.ncbi.nlm.nih.gov/pubmed/29499533

Clinical evaluation of fullerene-C60 dissolved in squalane for anti-wrinkle cosmetics.

The wrinkle and skin-surface roughness features were calculated and statistically analyzed. Subsequently, trans-epidermal water loss (TEWL), moisture levels of the stratum corneum, and visco-elasticity (suppleness: RO and elasticity: R7) were measured on cheeks by instrumental analysis. LF-SQ cream enhanced the skin moisture and the anti-wrinkle formation. LF-SQ cream that was applied on a face twice daily was not effective at 4th week, but significantly more effective than the placebo at 8th week (p < 0.05) without severe side effects.

https://www.ncbi.nlm.nih.gov/pubmed/21137794

Fullerene Nanomaterials Inhibit the Allergic Response

…fullerenes are capable of inhibiting MC and PBB allergic responses in vitro and anaphylaxis in vivo and suggests these molecules have previously unrecognized antiallergic properties. Fullerenes may represent a new way to control diseases largely influenced by these cells including type I hypersensitivity (anaphylaxis, hay fever, etc) (11), asthma (56), arthritis (57), multiple sclerosis (58), and other autoimmune diseases (59).

http://www.jimmunol.org/content/179/1/665.long

Fullerene-C60/liposome complex: Defensive effects against UVA-induced damages in skin structure, nucleus and collagen type I/IV fibrils, and the permeability into human skin tissue.

UVA-caused corneum scaling and disruption of epidermis layer were detected by scanning electron microscopy. Breakdown of collagen type I/IV, DNA strand cleavage and pycnosis/karyorrhexis were observed in vertical cross-sections of UVA-irradiated skin models visualized with fluorescent immunostain or Hoechst 33342 stain. These skin damages were scarcely repressed by liposome alone, but appreciably repressed by Lpsm-Flln of 250 ppm, containing 0.75 ppm of C60-equivalent to a 1/3300-weight amount vs. the whole liposome.

https://www.ncbi.nlm.nih.gov/pubmed/20036139

Inhibition of sebum production and Propionibacterium acnes lipase activity by fullerenol, a novel polyhydroxylated fullerene: Potential as a therapeutic reagent for acne

…It was also found that fullerenol has inhibitory activity against P. acnes lipase. These results suggest that fullerenol could be a beneficial skin care reagent for controlling acne vulgaris by suppressing sebum in the inflammatory response and by reducing P. acnes lipase activity.
(PDF) Inhibition of sebum production and Propionibacterium acnes lipase activity by fullerenol, a novel polyhydroxylated fullerene: Potential as a therapeutic reagent for acnehttps://www.researchgate.net/publication/233802771_Inhibition_of_sebum_production_and_Propionibacterium_acnes_lipase_activity_by_fullerenol_a_novel_polyhydroxylated_fullerene_Potential_as_a_therapeutic_reagent_for_acne [accessed Jun 11 2018].

Improvement of acne vulgaris by topical fullerene application: unique impact on skin care

Oxidative stress plays a major role in acne formation, suggesting that oxygen radical scavengers are potential therapeutic agents….fullerene inhibits sebum production, suggesting that fullerene suppresses acne through decreasing neutrophil infiltration and sebum production. After treatment for 8 weeks, the water content of the skin significantly https://www.sciencedirect.com/science/article/pii/S154996341000300X

Skin intervention of fullerene-integrated nanoemulsion in structural and collagen regeneration against skin aging

Despite the fact that intrinsic oxidative stress is inevitable, the extrinsic factor such as ultraviolet radiation enhances reactive oxygen species (ROS) generation resulting in premature skin aging. Nanoemulsion was loaded with fullerene, a strong free radical scavenger, and its efficacy to provide protection and regenerative effect against ROS-induced collagen breakdown in human skin was studied….  Biophysical characteristics of skin revealed that skin hydration was increased significantly … and the water was able to contain within the stratum corneum without any increased in transepidermal water loss. In the in vitrosafety evaluation, fullerene nanoemulsion showed no acute toxicity on 3T3 fibroblast cell line for 48 h and no indication of potential dermal irritation. Hence, the fullerene nanoemulsion may assist in protecting collagen from breakdown with cosmeceutical benefit. https://www.sciencedirect.com/science/article/pii/S092809871500024X

Scalp care and Hair Growth

it became clear that hair growth rate became 16% faster by as early as after six months. From this result, it was confirmed that fullerene could increase hair growth rate. This was believed to be caused by protecting the cells around the hair follicle from the active oxygen.

http://www.vc60.com/en/tech/effect/hairgrowth.html

Fullerene nanomaterials potentiate hair growth

Hair loss is a common symptom resulting from a wide range of disease processes and can lead to stress in affected individuals. The purpose of this study was to examine the effect of fullerene nanomaterials on hair growth…. paralleled by a significant increase in the number of hair follicles in fullerene-treated mice as compared with those mice treated with vehicle only. The fullerenes also increased hair growth in human skin sections maintained in culture. These studies have wide-ranging implications for those conditions leading to hair loss, including alopeciachemotherapy, and reactions to various chemicals.

https://www.sciencedirect.com/science/article/pii/S1549963408001512

Anti-inflammatory effect of fullerene C60 in a mice model of atopic dermatitis.

CONCLUSIONS: We suppose that nC60 treatment shifts immune response from Th2 to Th1 and restores to some extent the function of the skin barrier. This approach can be a good alternative to the treatment of allergic and other inflammatory diseases.

https://www.ncbi.nlm.nih.gov/pubmed/26810232

This Website, IPAC, from Russia has some of the most extensive listings of studies and papers on C60:

http://ipacom.com/index.php/ru/publikatsii/biologicheskie-svojstva 

Defensive Effects of Fullerene-C60 Dissolved in Squalane Against the 2,4-Nonadienal-Induced Cell Injury in Human Skin Keratinocytes HaCaT and Wrinkle Formation in 3D-Human Skin Tissue Model

he scanning electron microscopy demonstrated that NDA caused wrinkles and abnormal scales on keratinocytes of 3D-human skin tissue model, and structural homogeneity of the interstratum was broken, any of which were, however, markedly suppressed with LF-SQ. Squalane alone exhibited defensive effect against the skin tissue injury to some extent, but which was inferior to LF-SQ. LF-SQ might effectively capture and scavenge lipid radicals generated inside the cell membrane, because squalane acts as a lipophilic carrier of C60. C60 dissolved in squalane can be expected to serve as a cosmeceutical ingredient for anti-wrinkle formation.
Defensive Effects of Fullerene-C60… (PDF Download Available).

https://www.researchgate.net/publication/44627828_Defensive_Effects_of_Fullerene-C60_Dissolved_in_Squalane_Against_the_24-Nonadienal-Induced_Cell_Injury_in_Human_Skin_Keratinocytes_HaCaT_and_Wrinkle_Formation_in_3D-Human_Skin_Tissue_Model?enrichId=rgreq-9306ca07687fce0a93f536db7c9978ec-XXX&enrichSource=Y292ZXJQYWdlOzQ0NjI3ODI4O0FTOjE2MDMzOTYwMTY2NjA0OEAxNDE1MjM5MzQ4NDI1&el=1_x_3&_esc=publicationCoverPdf [

C60 reduces the bioavailability of mercury in aqueous solutions

The effects of C60 on mercury bioavailability and sorption were investigated at different C60 dosages, reaction times, and pH ranges…  In addition, lowering the pH from 7.2 to 5.8 decreased mercury bioavailability due likely to the increase in mercury’s association with C60. These results suggest that C60 may be useful in capturing soluble mercury and thus reducing mercury biotoxicity.

CHEM14252

PRISTINE C60 FULLERENES INHIBIT THE RATE OF TUMOR GROWTH AND METASTASIS

C60 FULLERENES INHIBIT THE RATE OF TUMOR GROWTH

CARDIOVASCULAR EFFECTS OF FULLERENE DERIVATIVES:

A REVIEW OF CURRENT EVIDENCE

c60-cardiovascular-health

The polyhydroxylated fullerene derivative C60 (OH)24 protects mice from ionizing-radiation-induced immune and mitochondrial dysfunction

C60-gamma-radiation-protection

Fullerene-based antioxidants and neurodegenerative disorders

fullerenes-help-familial-als

Toxicity of pristine versus functionalized fullerenes: Mechanisms of cell damage and the role of oxidative stress

toksicnostcistihvsfunkcionalizovanihfulerenatox.arch.

 

Effect of buckminsterfullerenes on cells of the innate and adaptive immune system: An in vitro study with human peripheral blood mononuclear cells

 Both fullerenes did not influence T cell reactivity, with no enhanced expression of CD69 and production of T cell cytokines observed, the CD4/CD8 ratio remaining unaffected. In contrast, they significantly enhanced the release of IL-6 and CD69-expression by CD56 positive natural killer cells. PBMC, which had been cultured together with the three recall antigens were not affected by both fullerenes at all. These data indicate that fullerenes do not interact with T cell reactivity but may activate cells of the innate immune system. Furthermore, they seem to act only on ‘naïve’ cells, which have not been prestimulated with recall antigens

Effect of buckminsterfullerenes on cells of the innate and adaptive immune system: An in vitro study with human peripheral blood mononuclear cells

 Nanomedicine has become one of the most promising areas of nanotechnology, while many have claimed its therapeutic use against cancer, human immunodeficiency virus (HIV), and neurodegenerative disorders. Water-soluble C(60) fullerene derivatives that come from chemical modification largely enhance the biological efficacy. The blood-brain barrier (BBB) is a physical barrier composed of endothelial tight junctions that restrict the paracellular permeability. A major challenge facing neuropharmacology is to find compounds that can be delivered into the brain through the bloodstream. Fullerene C(60) was demonstratively able to cross the BBB by hybridizing a biologically active moiety dyad, which provides a promising clue as a pharmacological therapy of neural disorders.

Fullerenol C 60 (OH) 36 protects human erythrocyte membrane against high-energy electrons